The 5th Vulnerable Plaque Symposium

Agenda *

7:00 am – 7:50 am Breakfast and Onsite Registration

8:00 am
Welcome                            Morteza Naghavi, MD
                                                     AEHA, Houston, TX, USA

8:05 am – 8:15 am
Opening Remarks A New Era in Cardiology; Diagnosis and Treatment of
Vulnerable Patients

                                                     Remarks by: James T. Willerson, MD
                                                     University of Texas Houston and
                                          Texas Heart Institute, Houston, TX, USA

Remarks by: Douglas Zipes, MD
Indiana University, Indianapolis, IN, USA

Scientific Session I

Scientific Presentations

Chair: Peter Libby, MD
Harvard Medical School, Boston, MA

Co-Chairs:

James Muller, MD
Harvard Medical School, Boston, MA., USA

Silvia Priori, MD, PhD
University of Milan, Italy

Wolfgang Koenig, MD, PhD
University of Ulm Medical Center, Germany

8:15 am - 8:25 am                    From Vulnerable Plaques to Vulnerable Patients: A
                                                       Call for New Definitions and Risk Stratification
                                                       Strategies – Presenting a consensus statement from
                                                       opinion leaders in Cardiology.

                                            Morteza Naghavi, MD
                                            University of Texas Houston and
                                            Texas Heart Institute, Houston, TX, USA

Q & A 5 minutes

8:30 am - 8:40 am Besides Vulnerable Plaque, What Defines Patients’ Risk and Final Outcome?
1- Vulnerable (Thrombogenic) Blood

Juan Jose Badimon, MD (Powerpoint)
Mount Sinai Hospital, New York, NY, USA

Q & A 5 minutes

8:45 am - 9:00 am Besides Vulnerable Plaque, What Defines Patients’ Risk and Final Outcome?
2- Vulnerable (Arrhythmogenic) Myocardium

K. E. Juhani Airaksinen, MD (Powerpoint)
University of Turku, Finland

Q & A 5 minutes

9:05 am - 9:30 am Future directions to evaluate patients’ overall cumulative vulnerability index, based on plaque, blood and myocardium vulnerability scores.

Discussion and Conclusion by the Chairs

Session II
Clinical Discussions
Non-Invasive Strategies

9:30 am – 10:30 am

Chair: Robert Bonow, MD
University of Chicago, IL, USA

Co-Chairs:
Salim Yusuf, MD
McMaster Clinic, Ontario, Canada

Atillio Maseri, MD
Universita Vita-Salute San Raffaele, Milan, Italy

Thom Brady, MD
Harvard Medical School, Boston, MA, USA

9:30 am - 9:45 am Patients with normal LDL and high CRP are at risk. How can CRP change your practice?

Paul Ridker, MD
Harvard Medical School, Boston, MA, USA

Q & A 5 minutes

9:50 am - 10:05 am Patients with high CRP and high calcium score are at higher risk. How can calcium score improve your practice?

John Rumberger, MD, PhD (Powerpoint)
Mayo Clinic and Foundation, Rochester, MN, USA

Q & A 5 minutes

10:10 am - 10:25 am Fast CT Angiography on a fast track to your practice: promises and limitations.

Stephen Achenbach, MD (Powerpoint)
Universität Erlangen-Nürnberg, Germany

Q & A 5 minutes

10:30 am - 10:45 am CRP, Calcium Score, Non-Invasive CT Angiography, and MRI Plaque Characterization. How to use them along with traditional risk factors?

Valentin Fuster, MD
Mount Sinai Medical Center, New York, NY, USA

Q&A 5 minutes

10:50 am - 11:00 am Discussion and conclusion by the Chairs

Scientific Session III
Case Presentations / Discussions
Invasive Strategies

11:00 am – 12:30 pm

Chair: Martin Leon, MD
Lenox Hill Hospital, New York, NY, USA

Co-Chairs:
Antonio Colombo
MDEMO Centro Cuore Columbus, Milan, Italy

Peter Fitzgerald, MD, Phd
Stanford University, CA, USA

Jeffrey Moses, MD
Lenox Hill Hospital, New York, NY, USA

                                                Jeffrey J. Popma
                                                            Brigham and Women’s Hospital, Boston, MA

Featured Presentation - Live Case

Who is a candidate for coronary thermography?

Live Case Presentation.

Christodoulos Stefanadis, MD
Athens Medical School, Greece, USA

This patient’s temperature has increased 0.5° C in proximal LAD without luminal stenosis. What should I do?

Live / Video Case Presentation.

Raimund Erbel, MD
University Clinic Essen, Germany

Who is a candidate for OCT or palpography and how to interpret the results?

Live / Video Case Presentation

Patrick Serruys, MD
Thoraxcenter, Amsterdam, The Netherlands

Lunch

12:30 pm - 1:00 pm

Boxed lunches distributed.

Session IV
Debates over hot topics

1:00 pm – 2:00 pm

Chair: Greg Stone, MD
Lenox Hill Hospital, New York, NY, USA

Co-Chairs:
Renu Virmani, MD
US Armed Forces, MD, USA

James Zidar, MD
Duke University, NC, USA

Paolo Raggi, MD
Tulane University School of Medicine, New Orleans, LA, USA

Paul Tierstein
Scripps Clinic, La Jolla, CA, USA

Debate I

1:00 pm - 1:30 pm More than 50% of coronary events are caused by non-stenotic lesions. Therefore, in the era of drug-eluding stents, we should stent all non-stenotic lesions, detected by thermography or other techniques.

Agree: Roxana Mehran, MD 10 minutes
Lenox Hill Hospital, New York, NY

Disagree: Robert Schwartz, MD 10 minutes
Mayo Clinic, Minneapolis, MN, USA

Discussion by the Panel 10 minutes

Debate II

1:30 pm - 2:00 pm Subjects with calcium scores above 400 are 10 times more at risk than age-matched patients with calcium scores below 10; therefore, calcium imaging should be routine.

Agree: Matt Budoff, MD (Powerpoint) 10 minutes
UCLA, Los Angles, CA, USA

Disagree: Pedro Moreno, MD 10 minutes
University of Kentucky, KY, USA

Discussion by the Panel 10 minutes

Debate III Statins are NOT good or fast enough; they are
overrated!

2:00 pm – 2:30 pm Ward Casscells, MD (Powerpoint) 10 minutes
University of Texas-Houston, Texas Heart Institute, TX, USA

Statins are good and fast enough; physician and patient compliance should be our focus!

William Insull, MD (Powerpoint) 10 minutes
Baylor College of Medicine, Houston, TX, USA

Discussion by the Panel 10 minutes

Session V
Emerging Therapies

2:30 pm - 3:30 pm

Chair: Scott Grundy, MD
University of Texas-Southwestern, TX, USA

Co-Chairs:
Erling Falk, MD
Aarhus University Hospital, Denmark

Greg Brown, MD, PhD
University of Washington, Seattle, WA, USA

Peter Stone, MD
Harvard Medical School, Boston, MA, USA

2:30 pm – 3:30 pm What are our options for pan-arterial treatment of vulnerable patients?

Rapid Stabilization with Apo A-1 Milano

Prediman K. Shah, MD 15 minutes
Cedars-Sinai Medical Center , Los Angeles, CA, USA

Intravascular Photodynamic Therapy

Ron Waksman, MD 15 minutes
Cardiovascular Research Institute, Washington DC, USA

Intrapericardial and Advetitial Drug Delivery

Keith March, MD, PhD 15 minutes
Indiana University, Indianapolis,IN, USA

Discussion by the Panel 10 minutes

3:30 pm – 4:00 pm

Coffee Break

Poster Presentation

Open 9 am – 6 pm

Posters from academia and industry will be available
throughout the day.

Poster presenters are required to be present during the
break.

6:00 pm – 7:00 pm Cocktails and Social Drink

Dinner / Award Reception at Hyatt Regency McCormick Place

AEHA Dinner Reception

(A detailed agenda for Dinner reception will be posted later.)

7:00 pm - 9:00 pm On the 99^th floor of Sears Tower

Award Presentations:

The 5^th AEHA Vulnerable Plaque Lifetime Achievement Award
The 3^rd AEHA James T. Willerson Vulnerable Plaque Young Investigator Prize
The 3^rd AEHA James E. Muller Vulnerable Plaque New Investigator Prize

*Coffee, tea, cold drinks, and cookies are served during the conference.

*Preliminary agenda is subject to change